Document And Entity Information
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
Expected dividend yield
IPR&D - celiprolol
us-gaap_NontradeReceivables
Nontrade Receivables
Note To Financial Statement Details Textual
Significant Accounting Policies
Share-Based Payment Arrangement, Option, Exercise Price Range [Table Text Block]
Maturities of investments
Note C - Segment Information
Note D - Inventories
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
Risk-free interest rate
us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Note E - Accounts and Other Receivables
us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five
Note F - Prepaid Expenses and Other Current Assets
Note G - Property and Equipment
Note H - Accounts Payable and Accrued Expenses
Note I - Debt Obligations
Prepaid expenses
Note L - Stock and Warrants
Income Tax Disclosure [Text Block]
Note M - Stock-based Compensation
Other current assets
zvra_EmployeeStockPurchasePlanMaximumNumberOfIssuableShares
Employee Stock Purchase Plan, Maximum Number of Issuable Shares (in shares)
Maximum number of shares that may be issued under Employee Stock Purchase Plan.
Note N - Fair Value of Financial Instruments
Note O - Income Taxes
us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents
Cash
Note P - Net Loss Per Share
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
Expected volatility
Inventory
Note Q - Leases
us-gaap_LiabilitiesCurrent
Total current liabilities
Schedule of Maturities of Long-Term Debt [Table Text Block]
Note S - Goodwill & Intangible Assets
Note T - Merger
Note C - Segment Information - Operating Segment Results (Details)
us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
Expected term (in years) (Year)
Note D - Inventories - Summary of Inventory (Details)
Other current liabilities
us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable
Business Combination, Consideration Transferred, Equity Interests Issued and Issuable
Schedule of Unvested Restricted Stock Units Roll Forward [Table Text Block]
Note E - Accounts and Other Receivables - Accounts and Other Receivables (Details)
Note F - Prepaid Expenses and Other Current Assets - Components of Prepaid Expenses and Other Current Assets (Details)
us-gaap_BusinessCombinationConsiderationTransferred1
Business Combination, Consideration Transferred
Note G - Property and Equipment - Components of Property and Equipment (Details)
Note G - Property and Equipment - Estimated Useful Lives of Property and Equipment (Details)
Note H - Accounts Payable and Accrued Expenses - Accounts Payable and Accrued Expenses (Details)
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Note I - Debt Obligations - Aggregate Principal Amount (Details)
us-gaap_BusinessCombinationConsiderationTransferredOther1
Business Combination, Consideration Transferred, Other
Note I - Debt Obligations - Future Minimum Principal Payments (Details)
Note L - Stock and Warrants - Reserved Authorized Shares of Common Stock for Future Issuance (Details)
Note L - Stock and Warrants - Common Stock Activity (Details)
Note M - Stock-based Compensation - Stock-based Compensation Expense (Details)
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Note M - Stock-based Compensation - Black-Scholes Option-pricing Model (Details)
Note M - Stock-based Compensation - Schedule of Stock Option Activity (Details)
us-gaap_BusinessAcquisitionSharePrice
Business Acquisition, Share Price (in dollars per share)
Granted, weighted-average grant date fair value (in dollars per share)
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
Note M - Stock-based Compensation - Information Regarding Currently Outstanding and Exercisable Options (Details)
Arimoclomol Purchase Agreement [Member]
Represents Arimoclomol Purchase Agreement.
Vested, weighted-average grant date fair value (in dollars per share)
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue
Note M - Stock-based Compensation - Nonvested Stock Option Awards (Details)
Note M - Stock-based Compensation - Restricted Stock Unit Activity (Details)
Forfeited, weighted-average grant date fair value (in dollars per share)
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
Unvested balance, weighted-average grant date fair value (in dollars per share)
Unvested balance, weighted-average grant date fair value (in dollars per share)
Note N - Fair Value of Financial Instruments - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)
US Treasury Securities [Member]
Forfeited (in shares)
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
Note N - Fair Value of Financial Instruments - Fair Value Assumptions for Warrant Liabilities (Details)
Foreign currency translation adjustment
Note N - Fair Value of Financial Instruments - Reconciliation of Beginning and Ending Balances for Derivative and Warrant Liability Measured at Fair Value on Recurring Basis (Details)
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
Unvested balance (in shares)
Unvested balance (in shares)
Note O - Income Taxes - Schedule of Reconciliation of Difference Between Benefit for Income Taxes and Income Taxes at Statutory U.S. Federal Income Tax Rate (Details)
zvra_AssetAcquisitionConsiderationTransferredEstimatedReserveLiability
Asset Acquisition, Consideration Transferred, Estimated Reserve Liability
Represents estimated reserve liability for asset acquisition consideration transferred.
Note O - Income Taxes - Components of Net Deferred Tax Assets and Liabilities (Details)
Note P - Net Loss Per Share - Anti-dilutive Securities (Details)
Note P - Net Loss Per Share - Earnings Per Share (Details)
zvra_ContractWithCustomerClawbackLiability
Contract with Customer, Clawback Liability
Represents clawback liability for contract with customer
Granted (in shares)
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
Note Q - Leases - Lease Cost (Details)
Vested (in shares)
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod
Note Q - Leases - Supplement Cash Flow Information Related to Leases (Details)
Vested and expected to vest, weighted average remaining contractual term (Year)
Note Q - Leases - Supplement Balance Sheet Information Related to Lease (Details)
Note Q - Leases - Supplement Balance Sheet Information Related to Lease (Details) (Parentheticals)
Note Q - Leases - Maturities of Lease Liabilities (Details)
Schedule of Nonvested Restricted Stock Units Activity [Table Text Block]
Note S - Goodwill & Intangible Assets - Amortization of Intangible Assets (Details)
Other comprehensive income (loss):
Note T - Merger - Estimates and Assumptions Related to Fair Value of Assets and Liabilities Acquired (Details)
Note T - Merger - Reconciliation of Contingent Consideration Liabilities (Details)
Vested and expected to vest, number of options (in shares)
Vested and expected to vest, weighted average exercise price (in dollars per share)
Notes To Financial Statements
Vested and expected to vest, aggregate intrinsic value
Notes To Financial Statements [Abstract]
us-gaap_PaymentsToAcquireOtherInvestments
Purchases of investments
Exercisable, weighted average exercise price (in dollars per share)
Exercisable, weighted average remaining contractual term (Year)
Exercisable, aggregate intrinsic value
us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Exercisable, number of options (in shares)
us-gaap_PaymentsToAcquireNotesReceivable
Payments to Acquire Notes Receivable
Line of credit payable
Outstanding, weighted average remaining contractual term (Year)
Outstanding, aggregate intrinsic value
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value (in dollars per share)
Number of unvested shares (in shares)
Retirement Plan Name [Axis]
Retirement Plan Name [Domain]
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
Outstanding, weighted average exercise price (in dollars per share)
Outstanding, weighted average exercise price (in dollars per share)
zvra_SharesAndWarrantsIssuedPricePerShare
Shares and Warrants Issued, Price Per Share (in dollars per share)
The price per share of shares and warrants issued.
us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent
Total accounts payable and accrued expenses
Accounts payable and accrued expenses
Canceled or forfeited, weighted average exercise price (in dollars per share)
Expired, weighted average exercise price (in dollars per share)
JMP and RBCCM [Member]
Represents JMP Securities LLC ("JMP") and RBC Capital Markets, LLC ("RBCCM").
Goodwill and Intangible Assets Disclosure [Text Block]
Granted, weighted average exercise price (in dollars per share)
Exercised or released, weighted average exercise price (in dollars per share)
zvra_EquityDistributionAgreementMaximumAggregateOfferingPrice
Equity Distribution Agreement, Maximum Aggregate Offering Price
The maximum aggregate offering price under the equity distribution agreement.
zvra_EquityDistributionAgreementCommissionFeePercentageOfGrossSales
Equity Distribution Agreement, Commission Fee, Percentage of Gross Sales
The percentage of gross sales for commission fee under the equity distribution agreement.
Accounts payable
Proceeds from insurance financing arrangements
Represents proceeds from insurance financing arrangements.
Options outstanding, number of shares (in shares)
Outstanding, number of options (in shares)
Outstanding, number of options (in shares)
Loans, Notes, Trade and Other Receivables Disclosure [Text Block]
Expired, number of options (in shares)
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]
Other accrued expenses
zvra_PaymentsOfPrincipalOnInsuranceFinancingArrangements
Payments of principal on insurance financing arrangements
Represents payments of principal on insurance financing arrangements.
Accrued payroll
us-gaap_PolicyTextBlockAbstract
Accounting Policies
us-gaap_NotesIssued1
Issuance of secured promissory note for the Merger (Note T)
Accrued professional fees
us-gaap_StockIssued1
Issuance of common stock in connection with the Merger (Note T)
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedCompensationCost
Share-Based Payment Arrangement, Accelerated Cost
Indefinite-Lived Intangible Assets [Axis]
us-gaap_PaymentsToAcquireIntangibleAssets
Payments to Acquire Intangible Assets
Payment of royalty to XOMA
Indefinite-Lived Intangible Assets, Major Class Name [Domain]
us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Purchases of property and equipment
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized (in shares)
Supplemental disclosure of noncash investing activities:
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized (in shares)
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Liabilities and stockholders’ equity
us-gaap_LossContingencyAccrualAtCarryingValue
Loss Contingency Accrual
Weighted average number of shares of common stock outstanding:
Operating lease liabilities
us-gaap_Assets
Total assets
Supplemental cash flow information:
Patents [Member]
zvra_IncomeTaxExaminationNumberOfReturnsUnderExamination
Income tax returns under examination
Number of returns under examination
Plan Name [Axis]
Plan Name [Domain]
Compensation and Employee Benefit Plans [Text Block]
In Process Research and Development [Member]
us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Other Current Assets [Text Block]
us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic
Net loss
us-gaap_SubleaseIncome
Less: sublease income
Other prepaid expenses and current assets
Amount of prepaid expenses and current assets classified as other.
Mergers, Acquisitions and Dispositions Disclosures [Text Block]
Computer and Hardware [Member]
Long-lived, depreciable assets that are used in the creation, maintenance, and utilization of information systems.
Laboratory Equipment [Member]
Tangible laboratory property used to produce good and services.
Finite-Lived Intangible Assets by Major Class [Axis]
Share-Based Payment Arrangement [Text Block]
Finite-Lived Intangible Assets, Major Class Name [Domain]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Property, Plant and Equipment, Useful Life [Table Text Block]
Tabular disclosure of useful lives of physical assets used in the normal conduct of business and not intended for resale.
ATM Agreement Sales [Member]
Represents for At-the-Market Agreement Sales.
Schedule of Business Acquisitions by Acquisition, Contingent Consideration [Table Text Block]
Business Description and Basis of Presentation [Text Block]
Award Type [Domain]
Award Type [Axis]
Segment net loss
Net loss
Net loss
Net loss, basic and diluted
us-gaap_FiniteLivedIntangibleAssetsNet
Finite-Lived Intangible Assets, Net
Intangible assets, net
Restricted Stock Units (RSUs) [Member]
Deferred adjustment and rate change
Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to deferred adjustment and rate change.
Performance Shares [Member]
Share-Based Payment Arrangement [Member]
Warrant [Member]
Inventory [Axis]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
zvra_IncomeTaxExpenseBenefitNoncashAdjustment
Income tax expense
The amount of noncash adjustment due to income tax expense (benefit).
Inventory [Domain]
Antidilutive Securities [Axis]
Antidilutive Securities, Name [Domain]
Uncertain tax position
Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to uncertain tax position.
Underwriting Agreement [Member]
Represents the information pertaining to the underwriting agreement.
us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill
Indefinite-Lived Intangible Assets (Excluding Goodwill)
zvra_ProceedsFromIssuanceOfCommonStockNet
Proceeds from Issuance of Common Stock, Net
The cash inflow from issuance of common stock, net of cash paid for issuance cost.
Commitments and Contingencies Disclosure [Text Block]
us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
Less: accumulated depreciation and amortization
Property, Plant and Equipment, Net
Property and equipment, net
Goodwill acquired
Goodwill
Property and equipment, gross
Derivative Instrument [Axis]
Derivative Contract [Domain]
Cash flows from investing activities:
zvra_FinancingReceivableMaximumLimit
Financing Receivable, Maximum Limit
The maximum limit of the financing receivable.
Acer Therapeutics Inc [Member]
Represents Acer Therapeutics Inc.
Bridge Loan [Member]
Earnings Per Share [Text Block]
zvra_ClassOfWarrantsOrRightExercisedDuringPeriod
Class of Warrants or Right, Exercised During Period (in shares)
The number of warrants or rights exercised during period.
us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Accounts payable and accrued expenses
Income tax expense
us-gaap_IncomeTaxExpenseBenefit
Income tax expense
Consolidation, Variable Interest Entity, Policy [Policy Text Block]
SWK Loans [Member]
Represents the SWK Loans.
zvra_DebtInstrumentInterestRateStatedPercentageIfUnpaidWithinSixMonths
Debt Instrument, Interest Rate, Stated Percentage, If Unpaid Within Six Months
Contractual interest rate for funds borrowed, under the debt agreement, if unpaid within six months.
Nantahala Note [Member]
Represents the Nantahala Note.
zvra_SeveranceCostsRecognized
Severance Costs Recognized
The amount of severance costs recognized.
zvra_DebtInstrumentInterestSharesConsecutiveTradingDaysForCalculationOfVWAP
Debt Instrument, Interest, Shares, Consecutive Trading Days For Calculation of VWAP (Day)
The consecutive trading days for calculation of VWAP for interest to be paid in shares on debt instrument.
zvra_DebtInstrumentInterestRateIncreaseInStatedPercentageIfUnpaidWithinSixMonths
Debt Instrument, Interest Rate, Increase in Stated Percentage, If Unpaid Within Six Months
Increase in the contractual interest rate for funds borrowed, under the debt agreement, if unpaid within six months.
zvra_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuableConversionRatio
Business Combination, Consideration Transferred, Equity Interests Issued and Issuable, Conversion Ratio
Conversion ratio of equity interests of the acquirer, including instruments or interests issued or issuable in consideration for the business combination.
XOMA License Agreement [Member]
Information pertaining to the type of arrangement.
zvra_VwapConsecutiveTradingDays
VWAP, Consecutive Trading Days (Year)
The consecutive trading days for VWAP.
Right-of-use liability
Deferred tax assets related to right-of-use assets.
Warrants [Policy Text Block]
Represents the policy for warrants.
Aquestive Therapeutics [Member]
Represents Aquestive Therapeutics (formerly known as MonoSol Rx, LLC).
AZSTARYS License Agreement [Member]
Information pertaining to the litigation.
zvra_AssetAcquisitionSharePrice
Asset Acquisition, Share Price (in dollars per share)
The share price of equity interest issued in asset acquisition.
Right-of-use asset
Deferred liabilities related to right-of-use.
Wells Fargo Bank, N.A. [Member]
Represents the "Wells Fargo Bank, N.A."
us-gaap_DefinedContributionPlanEmployerDiscretionaryContributionAmount
Defined Contribution Plan, Employer Discretionary Contribution Amount
License Agreement and Termination Agreement [Member]
Represents License Agreement and Termination Agreement.
Marathon Convertible Notes [Member]
Represents the Marathon Convertible Notes.
us-gaap_DefinedContributionPlanEmployerMatchingContributionPercent
Defined Contribution Plan, Employer Matching Contribution, Percent of Employees' Gross Pay
zvra_MaximumRoyaltyObligation
Maximum Royalty Obligation
Amount of maximum royalty obligation.
Worldwide, Excluding Europe [Member]
Represents worldwide, excluding Europe.
Exercise Price Range One [Member]
The exercise price range one.
SWK Loans and Marathon Notes [Member]
Represents the SWK Loans and Marathon Notes.
Cash and cash equivalents
Relief [Member]
Represents Relief.
Interest expense
us-gaap_InterestExpenseNonoperating
Interest expense
zvra_MaximumRoyaltyPercentage
Maximum Royalty Percentage
Percentage of maximum royalty.
zvra_AdditionalPaymentOnFirstAnniversary
Addiitonal Payment on First Anniversary
Amount of additional payment on first anniversary.
us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities
Other liabilities
Exercise Price Range Two [Member]
The exercise price range two.
zvra_UpfrontPayment
Upfront Payment
Amount of upfront payment.
Exercise Price Range Three [Member]
The exercise price range three.
Stock based compensation expense
Share-Based Payment Arrangement, Expense
Exercise Price Range Four [Member]
The exercise price range four.
Exercise Price Range Five [Member]
The exercise price range five.
zvra_LineOfCreditFacilityMaximumBorrowingCapacityPercentageOfInvestments
Line of Credit Facility, Maximum Borrowing Capacity, Percentage of Investments
Percentage of investments outstanding for maximum borrowing capacity of the debt instrument.
Danish [Member]
Represents the taxing authority of Denmark.
Amendment Flag
us-gaap_ComprehensiveIncomeNetOfTax
Comprehensive loss
City Area Code
Use of Estimates, Policy [Policy Text Block]
New Accounting Pronouncements, Policy [Policy Text Block]
us-gaap_DebtInstrumentPeriodicPaymentInterest
Debt Instrument, Periodic Payment, Interest
us-gaap_TreasuryStockSharesAcquired
Common stock repurchased as a result of the Stock Repurchase Program (in shares)
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding (in shares)
Balance (in shares)
Balance (in shares)
Commave Therapeutics SA [Member]
Named other party that participates in a financial transaction. Examples include, but not limited to, the name of the financial institution.
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding (in shares)
Possible Future Issuances Under Employee Stock Purchase Plans [Member]
Represents possible future issuances under employee stock purchase plans.
Derivative and warrant liability
Derivative and Warrant Liability, Noncurrent
Noncurrent Carrying amount of derivative and warrant liability.
Current Fiscal Year End Date
us-gaap_DebtInstrumentBasisSpreadOnVariableRate1
Debt Instrument, Basis Spread on Variable Rate
us-gaap_DebtInstrumentInterestRateStatedPercentage
Debt Instrument, Interest Rate, Stated Percentage
Variable lease cost
Return to provision and deferred true-up
Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to return to provision and deferred true-up.
us-gaap_LeaseCost
Total lease costs
us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Prepaid expenses and other current assets
Operating leases
zvra_DeferredIncomeTaxAssetsLiabilities
Deferred tax assets less liabilities
Amount, before allocation of valuation allowance and after deferred tax liability and deferred tax asset attributable to deductible differences and carryforwards, without jurisdictional netting.
Document Fiscal Period Focus
Operating lease cost
Document Fiscal Year Focus
Short-term lease cost
Lease, Cost [Table Text Block]
Right-of-use assets obtained in exchange for lease liabilities
Finance leases
Document Period End Date
us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
Operating leases
Operating leases (in years) (Year)
Entity File Number
Entity Emerging Growth Company
us-gaap_DebtInstrumentFaceAmount
Debt Instrument, Face Amount
Document Type
Interim Period, Costs Not Allocable [Domain]
Entity Small Business
Entity Shell Company
Document Information [Line Items]
Document Information [Table]
Retirement Plan [Member]
The 401(k) retirement plan covering substantially all employees.
Profit Sharing Plan [Member]
The dicretionary profit sharing plan that covers all employees.
us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue
Balance
Balance
Nature of Expense [Axis]
Entity Public Float
Entity Filer Category
Debt Instrument [Axis]
Entity Current Reporting Status
Debt Instrument, Name [Domain]
Entity Voluntary Filers
Entity Well-known Seasoned Issuer
us-gaap_ImpairmentOfIntangibleAssetsFinitelived
Impairment of Intangible Assets, Finite-Lived
Variable Rate [Domain]
Change in fair value measurement
Amount of cumulative effect adjustment for financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.
Prime Rate [Member]
us-gaap_ImpairmentOfLongLivedAssetsHeldForUse
Impairment, Long-Lived Asset, Held-for-Use
zvra_FairValueAdjustmentOfPutOptionNetOfTax
Fair Value Adjustment of Put Option, Net of Tax
After tax amount of expense (income) related to adjustment to fair value of put option.
us-gaap_ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill
Impairment of Intangible Assets, Indefinite-Lived (Excluding Goodwill)
Schedule of Long-Term Debt Instruments [Table Text Block]
us-gaap_GoodwillImpairmentLoss
Goodwill, Impairment Loss
us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued
Issuance of warrants
Variable Rate [Axis]
Stock-based compensation expense
Statement of Comprehensive Income [Abstract]
us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables
Accounts and other receivables
Entity Tax Identification Number
Entity Central Index Key
Capitalized Contract Cost [Axis]
Entity Registrant Name
Capitalized Contract Cost [Domain]
Liability Class [Axis]
Fair Value by Liability Class [Domain]
Entity [Domain]
Legal Entity [Axis]
Entity Address, Address Line One
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Amortization of intangible assets
Amortization of Intangible Assets
ecd_NonRule10b51ArrTrmntdFlag
Non-Rule 10b5-1 Arrangement Terminated [Flag]
us-gaap_TreasuryStockValueAcquiredCostMethod
Shares repurchased as part of the Share Repurchase Program
Entity Address, City or Town
ecd_Rule10b51ArrTrmntdFlag
Rule 10b5-1 Arrangement Terminated [Flag]
ecd_Rule10b51ArrAdoptedFlag
Rule 10b5-1 Arrangement Adopted [Flag]
Entity Address, Postal Zip Code
Entity Address, State or Province
ecd_NonRule10b51ArrAdoptedFlag
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Material Terms of Trading Arrangement [Text Block]
us-gaap_TreasuryStockValue
Treasury stock, at cost
Entity Common Stock, Shares Outstanding
us-gaap_IncreaseDecreaseInOtherNoncurrentAssets
Other long-term assets
us-gaap_IncreaseDecreaseInInventories
Inventories
Trading Symbol
Common stock issued in connection with the Merger (Note T) (in shares)
Stock Issued During Period, Shares, Acquisitions (in shares)
Common stock issued as a result of the Employee Stock Purchase Plan (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans (in shares)
Local Phone Number
Issuance of common stock in connection with the Merger
Common stock issued as a result of stock options exercised (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period (in shares)
us-gaap_TableTextBlock
Notes Tables
Issuance of common stock as part of the Employee Stock Purchase Plan
Common stock issued in connection with restricted stock units (in shares)
Issuance of common stock for options exercised
Finance Lease, Right-of-Use Assets [Member]
Represents finance lease right-of-use assets.
Litigation Related to Merger [Member]
Represent litigation related to merger.
Common stock issued in connection with vesting of performance-based awards (in shares)
Selling, general and administrative
Selling, general and administrative
zvra_DebtInstrumentMinimumCashBalance
Debt Instrument, Minimum Cash Balance
Minimum cash balance required for debt instrument to be active.
Secured Overnight Financing Rate (SOFR) [Member]
Granted, number of options (in shares)
Measurement Input
Canceled or forfeited, number of options (in shares)
Line of Credit Facility, Lender [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
zvra_CommonStockRegisteredMaximumOfferingPrice
Common Stock Registered, Maximum Offering Price
Represents maximum offering price under common stock registered.
JMP [Member]
Represents JMP.
Common stock issued in connection with the Public Offering (Note B) (in shares)
Stock Issued During Period, Shares, New Issues (in shares)
Issuance of common stock in exchange for consulting services
Notes Payable Excluding Secured Promissory Note [Member]
Represents Notes Payable Excluding Secured Promissory Note
us-gaap_StockIssuedDuringPeriodSharesIssuedForServices
Common stock issued as compensation to third-parties (in shares)
Lender Name [Axis]
us-gaap_LiabilitiesAndStockholdersEquity
Total liabilities and stockholders' equity
UNITED STATES
Issuance of common stock
Stock Issued During Period, Value, New Issues
Underwriting Agreement and Over-allotment Option [Member]
Represents Underwriting Agreement and Over-allotment Option.
zvra_StockIssuableDuringThePeriod
Stock Issuable During the Period (in shares)
Number of stock issuable during the period.
Accumulated deficit
Accumulated other comprehensive income (loss)
Research and development
Research and development
Debt Disclosure [Text Block]
Measurement Input, Price Volatility [Member]
Change in assets and liabilities:
Measurement Input, Risk Free Interest Rate [Member]
Schedule of Authorized Shares of Common Stock Reserved for Future Issuance [Table Text Block]
Tabular disclosure of authorized shares of common stock reserved for future issuance.
us-gaap_DisclosureTextBlockAbstract
Notes to Financial Statements
Inventory Disclosure [Text Block]
Measurement Input, Expected Dividend Rate [Member]
Operating lease liabilities, less current portion
Measurement Input, Expected Term [Member]
Possible Future Issuances Under Equity Incentive Plans [Member]
Represents possible future issuances under equity incentive plans.
us-gaap_OperatingLeaseLiability
Lease liabilities
Total operating lease liabilities
Non-cash interest expense
Current portion of operating lease liabilities
Subsequent Events [Text Block]
Total operating lease right-of-use assets
Operating lease right-of-use assets
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue
Total lease payments
zvra_SharebasedCompensationArrangementBySharebasedPaymentAwardNumberOfSharesReservedForIssuanceIncrementalPercentageOfCapitalStockOutstanding
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Reserved for Issuance, Incremental Percentage of Capital Stock Outstanding
Represents the share based compensation arrangement by share based payment award number of shares reserved for issuance incremental percentage of capital stock outstanding.
us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
Less: future interest expense
Financing cash flows from finance leases
Repayment of principal on finance lease liabilities
2014 Equity Incentive Plan [Member]
Represents the two thousand fourteen equity incentive plan.
zvra_IncreaseInCommonStockReservedForIssuance
Increase in Common Stock Reserved for Issuance (in shares)
Amount of increase in common stock reserved for issuance.
Measurement Input Type [Axis]
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree
2027
Measurement Input Type [Domain]
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour
2028
us-gaap_UnrealizedGainLossOnInvestments
Unrealized Gain (Loss) on Investments
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive
2029
us-gaap_FinanceLeaseRightOfUseAsset
Property and equipment, net
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive
Thereafter
Acer Warrants [Member]
Represents the Acer warrants.
Net Investment in Lease, before Allowance for Credit Loss
2026
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo
zvra_CommonStockRegisteredShares
Common Stock Registered, Shares (in shares)
Shares registered as apart of an S-3 filing.
2027
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree
zvra_GainLossOnContingentConsiderationChangeInFairValue
Gain (Loss) on Contingent Consideration, Change in Fair Value
Represents the gain/(loss) on contingent consideration from the changes in fair value over the period.
2028
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
2025
2029
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
2026
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Segment Reporting, Policy [Policy Text Block]
Issuance of contingent value rights for the Merger (Note T)
The fair value of contingent value rights issued in noncansh financing activities.
2025
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths
The Investor Warrant [Member]
Represents the warrant held by the investor.
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Relief Therapeutics [Member]
Relates to Relief Therapeutics.
Warrants to Purchase Common Stock [Member]
Represents warrants to purchase common stock.
Other long-term assets
us-gaap_ShareBasedCompensation
Stock-based compensation expense
Deferred collaboration funding
Amount of liabilities incurred for deferred collaboration funding assumed on the acquisition date.
Accounts payable and accrued expenses
Amount of liability incurred for accounts payable and accrued expenses assumed at acquisition date.
us-gaap_FiniteLivedIntangibleAssetUsefulLife
Finite-Lived Intangible Asset, Useful Life (Year)
zvra_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOperatingLeaseLiabilities
Operating lease liabilities
Amount of liabilities incurred for operating leases assumed at the acquisition date.
Earnings Per Share, Policy [Policy Text Block]
Approved product - OLPRUVA
Amount of the approved product, OLPRUVA, acquired at the acquisition date.
zvra_DefinedContributionPlanRequisiteServicePeriod
Defined Contribution Plan, Requisite Service Period (Year)
Minimum period employees are required to perform services to become eligible under the defined contribution plan, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
Operating expenses:
Income Tax, Policy [Policy Text Block]
zvra_RoyaltyRevenuePercent
Royalty Revenue, Percent
Represents the royalty revenue expressed as a percentage.
Total assets
zvra_RevenueRecognitionMilestoneMethodAdditionalRevenueToBeRecognized
Revenue Recognition, Milestone Method, Additional Revenue to be Recognized
The amount of additional consideration to be recognized for the milestone or milestones.
us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments
Amortization (accretion) on investments
In Process Research and Development, Policy [Policy Text Block]
Research and Development Expense, Policy [Policy Text Block]
Securities at fair value, noncurrent
Depreciation and amortization expense
Depreciation and amortization expense
Depreciation, Depletion and Amortization
Total liabilities
CVR Liability [Member]
Represents the CVR liability.
us-gaap_SharesIssuedPricePerShare
Shares Issued, Price Per Share (in dollars per share)
Inventories, noncurrent
us-gaap_AssetsCurrent
Total current assets
zvra_FinanceLeaseCostTotal
Total finance lease cost
Represents total cost of fiance lease.
us-gaap_InvestmentsFairValueDisclosure
Investments, Fair Value Disclosure
Share-Based Payment Arrangement [Policy Text Block]
Equity [Text Block]
zvra_LesseeLeaseRemainingTermOfContract
Lessee, Lease, Remaining Term of Contract (Year)
Remaining term of lessee's lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.
Lease Disclosure [Text Block]
The entire disclosure for operating, finance, sale leaseback leases.
Weighted average fair value (in dollars per share)
Represents the weighted average fair value under fair value assumptions for warrant liabilities.
Change in fair value recognized in earnings
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Common stock, $0.0001 par value, 250,000,000 shares authorized, 55,246,401 shares issued and 53,670,709 shares outstanding as of December 31, 2024; 43,110,360 shares issued and 41,534,668 shares outstanding as of December 31, 2023
Adjustments to reconcile net loss to net cash used in operating activities:
Measurement Frequency [Axis]
Measurement Frequency [Domain]
Fair Value, Recurring [Member]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized (in shares)
Common stock, shares issued (in shares)
Common Stock, Shares, Issued (in shares)
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share (in dollars per share)
Schedule of Leases Cash Flow Information [Table Text Block]
Tabular disclosure of leases related to cash flow information.
Revenue from Contract with Customer [Policy Text Block]
Schedule of Leases Balance Sheet Information [Table Text Block]
Tabular disclosure of leases related to balance sheet.
Common shares reserved for future issuance (in shares)
us-gaap_DeferredTaxAssetsValuationAllowance
Valuation allowance
Statistical Measurement [Domain]
Term Loans Under Credit Agreement [Member
Represents term loans under credit agreement.
Operating cash flows from operating leases
Maximum [Member]
zvra_DebtInstrumentAvailableAmountUntilDecember312024
Debt Instrument, Available Amount Until December 31, 2024
Amount of debt available to be drawn until December 31, 2024.
Minimum [Member]
zvra_DebtInstrumentNetProductSalesPerformanceBenchmark
Debt Instrument, Net Product Sales Performance Benchmark
Amount of performance benchmark of net product sales under debt instrument.
zvra_DebtInstrumentBasisSpreadOnVariableRateWhenPerformanceBenchmarkMeet
Debt Instrument, Basis Spread on Variable Rate When Performance Benchmark Meet
Percentage points added to the reference rate to compute the variable rate on the debt instrument when performance benchmark meet.
Product and Service [Axis]
us-gaap_PaymentsForLegalSettlements
Payments for Legal Settlements
Operating cash flows from short-term leases
Product and Service [Domain]
zvra_DebtInstrumentAvailableAmountUntil18MonthsFollowingClosingDateMaximumEachDrawing
Debt Instrument, Available Amount Until 18 Months Following Closing Date, Maximum Each Drawing
Maximum each drawing for amount available under debt instrument to draw after 18 months of debt closing date.
Fair value adjustment related to derivative and warrant liability and CVR liability
zvra_FairValueAdjustmentOfWarrantsAndCvrLiability
Fair value adjustment related to warrant and CVR liability
Amount of expense (income) related to adjustment to fair value of warrant liability and CVR Liability
Operating cash flows from variable lease costs
Statistical Measurement [Axis]
zvra_DebtInstrumentAvailableAmountUntil18MonthsFollowingClosingDate
Debt Instrument, Available Amount Until 18 Months Following Closing Date
Amount of debt available until 18 months following closing date under debt instrument.
Litigation Case [Axis]
Litigation Case [Domain]
Operating and Finance Lease, Liability, Maturity [Table Text Block]
Tabular disclosure of undiscounted cash flows of operating and finance lease liability. Includes, but is not limited to, reconciliation of undiscounted cash flows to operating and finance lease liability recognized in statement of financial position.
Debt, Policy [Policy Text Block]
Undesignated preferred stock, $0.0001 par value, 10,000,000 shares authorized, no shares issued or outstanding as of December 31, 2024 or December 31, 2023
zvra_DebtInstrumentBasisSpreadOnVariableRateWhenPerformanceBenchmarkMeetInNextYear
Debt Instrument, Basis Spread on Variable Rate When Performance Benchmark Meet in Next Year
Percentage points added to the reference rate to compute the variable rate on the debt instrument when performance benchmark meet in next year.
Preferred stock, shares issued (in shares)
Preferred Stock, Shares Issued (in shares)
zvra_DebtInstrumentNetProductSalesPerformanceBenchmarkInNextYear
Debt Instrument, Net Product Sales Performance Benchmark in Next Year
Amount of performance benchmark of net product sales in next year under debt instrument.
Intangible Assets, Finite-Lived, Policy [Policy Text Block]
zvra_DebtInstrumentMaximumInterestPaymentPercentage
Debt Instrument, Maximum Interest Payment, Percentage
Maximum amount of interest payment allowed under debt instrument as a percentage.
Cash paid for interest
zvra_DebtInstrumentFloorRate
Debt Instrument, Floor Rate
Floor rate of debt instrument.
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
us-gaap_NoncurrentAssets
Long-Lived Assets
us-gaap_DeferredTaxAssetsOther
Other deferred tax assets
Geographical [Axis]
Property, Plant and Equipment Disclosure [Text Block]
Goodwill and Intangible Assets, Policy [Policy Text Block]
Geographical [Domain]
Property, Plant and Equipment [Table Text Block]
us-gaap_DeferredTaxAssetsGross
Total gross deferred tax assets
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized (in shares)
Europe [Member]
us-gaap_DeferredIncomeTaxLiabilities
Total gross deferred tax liabilities
OLPRUVA [Member]
Represents OLPRUVA.
zvra_LesseeLeaseOptionToTerminateTerm
Lessee, Lease, Option to Terminate, Term (Year)
Represents the terms of option to terminate lessee's lease.
Inventories, current
Inventory, Net
zvra_LesseeLeaseOptionToExtendMaximumTerm
Lessee, Lease, Option to Extend, Maximum Term (Year)
Represents maximum terms of option to extend lessee's lease.
Preferred stock, par value (in dollars per share)
Prepaid insurance
Work in progress
Total revenues
Revenue, net
Revenue from Contract with Customer, Including Assessed Tax
Fair Value, Inputs, Level 3 [Member]
us-gaap_ForeignCurrencyTransactionGainLossBeforeTax
Gain on foreign currency exchange rates
Finished goods
Fair Value Hierarchy and NAV [Domain]
Fair Value, Inputs, Level 1 [Member]
Fair Value, Inputs, Level 2 [Member]
us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment
Property and equipment
Fair Value Hierarchy and NAV [Axis]
Raw Materials
Property and equipment, useful lives (Year)
Property, Plant and Equipment, Useful Life (Year)
Cash flows from operating activities:
Accounts and other receivables
Total accounts and other receivables
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Statement [Line Items]
us-gaap_NumberOfOperatingSegments
Number of Operating Segments
Accounts receivable
Furniture and Fixtures [Member]
Stock-based compensation
us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
Additional paid-in capital
AOCI Attributable to Parent [Member]
Stockholders' equity:
Leasehold Improvements [Member]
Securities at fair value, current
Property, Plant and Equipment, Policy [Policy Text Block]
Other expense, net(a)
us-gaap_OtherNonoperatingIncomeExpense
Long-Lived Tangible Asset [Axis]
us-gaap_NonoperatingIncomeExpense
Total other (expense) income
Segment Reporting Disclosure [Text Block]
Long-Lived Tangible Asset [Domain]
us-gaap_DeferredTaxAssetsOperatingLossCarryforwards
Net operating loss carryforwards
Other (expense) income:
us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch
Research and development tax carryforward
Fair Value Disclosures [Text Block]
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
Cash and cash equivalents, beginning of period
Cash and cash equivalents, end of period
Inventory, Policy [Policy Text Block]
Assets [Abstract]
License [Member]
us-gaap_InvestmentIncomeInterest
Interest income
Effect of exchange rate changes on cash and cash equivalents
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
Net decrease in cash and cash equivalents
Over-Allotment Option [Member]
us-gaap_Liabilities
Total liabilities
us-gaap_NetCashProvidedByUsedInFinancingActivities
Net cash provided by financing activities
Commitments and contingencies (Note K)
Sale of Stock [Axis]
Sale of Stock [Domain]
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
us-gaap_OperatingIncomeLoss
Loss from operations
us-gaap_ContractWithCustomerLiabilityRevenueRecognized
Contract with Customer, Liability, Revenue Recognized
us-gaap_NetCashProvidedByUsedInOperatingActivities
Net cash used in operating activities
Prepaid expenses and other current assets
Total prepaid expenses and other current assets
us-gaap_NetCashProvidedByUsedInInvestingActivities
Net cash used in investing activities
us-gaap_DeferredTaxLiabilities
Net deferred tax liability
Intangibles
Counterparty Name [Axis]
Counterparty Name [Domain]
Consolidation Items [Domain]
Inventory obsolescence
Inventory Write-down
us-gaap_ContractWithCustomerLiability
Contract with Customer, Liability
Consolidation Items [Axis]
us-gaap_InterestPayableCurrentAndNoncurrent
Interest Payable
Intangible asset amortization
Investment, Policy [Policy Text Block]
Concentration Risk, Credit Risk, Policy [Policy Text Block]
us-gaap_CostsAndExpenses
Total operating expenses
us-gaap_PaymentsForRepurchaseOfCommonStock
Payment to repurchase shares as part of the Share Repurchase Program
Proceeds from Employee Stock Purchase Plan
Scenario [Domain]
Cost of Goods and Service [Policy Text Block]
Forecast [Member]
us-gaap_ProceedsFromWarrantExercises
Proceeds from Warrant Exercises
Retained Earnings [Member]
Undesignated Preferred Stock [Member]
Preferred stock that has been classified as undesignated.
Proceeds from issuance of common stock for options exercised
Proceeds from stock issuance
Scenario [Axis]
us-gaap_StateAndLocalIncomeTaxExpenseBenefitContinuingOperations
State and Local Income Tax Expense (Benefit), Continuing Operations
Treasury Stock, Common [Member]
Additional Paid-in Capital [Member]
Common Stock [Member]
us-gaap_IncomeTaxExaminationPenaltiesAndInterestAccrued
Income Tax Examination, Penalties and Interest Accrued
Equity Components [Axis]
MIPLYFFA [Member]
Pertains to MIPLYFFA.
Equity Component [Domain]
Class of Warrant or Right [Axis]
us-gaap_EffectiveIncomeTaxRateReconciliationGiltiPercent
Global intangible low-taxed income credit
Class of Warrant or Right [Domain]
Long-term debt
us-gaap_NotesPayable
Notes Payable
us-gaap_ClassOfWarrantOrRightOutstanding
Class of Warrant or Right, Outstanding (in shares)
us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
Loss before income taxes
us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)
Expiration of net operating loss deferred tax asset
Percentage of difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying domestic federal statutory income tax rate to pretax income (loss) from continuing operations, attributable to the expiration of net operating loss deferred tax asset.
us-gaap_PaymentsOfFinancingCosts
Payment of deferred financing costs
ICFR Auditor Attestation Flag
Capitalization, Royalty Expense [Member]
Pertains to capitalized costs.
us-gaap_LineOfCredit
Long-Term Line of Credit
State and Local Jurisdiction [Member]
us-gaap_DeferredFinanceCostsNet
Debt Issuance Costs, Net
Less: debt issuance costs
Income Tax Authority, Name [Axis]
Income Tax Authority, Name [Domain]
us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
Less: unamortized debt discount and debt issuance costs
us-gaap_DeferredRevenue
Deferred Revenue
Income Tax Jurisdiction [Axis]
Indirect Operating Costs [Member]
Information pertaining to the nature of the expense.
Income Tax Jurisdiction [Domain]
Direct Operating Costs [Member]
Information pertaining to the nature of the expense.
Domestic Tax Jurisdiction [Member]
Foreign Tax Jurisdiction [Member]
Public Offering [Member]
Sale of the entity's stock, including, but not limited to, initial public offering (IPO) and private placement.
Revenue from Contract with Customer [Text Block]
zvra_InventoryCurrentAndNoncurrentTotal
Total inventories
Represents inventory.
Document Annual Report
us-gaap_DebtInstrumentUnamortizedDiscountPremiumNet
Unamortized original issue (discount) premium
Cash and Cash Equivalents, Policy [Policy Text Block]
PRV Transfer Agreement [Member]
Pertains to the type of arrangement.
Receivable [Policy Text Block]
Entity Incorporation, State or Country Code
Notes payable
us-gaap_DebtInstrumentCarryingAmount
Total minimum payments
General and Administrative Expense [Member]
Accounting Policies [Abstract]
Significant Accounting Policies [Text Block]
Document Transition Report
Document Financial Statement Error Correction [Flag]
Entity Interactive Data Current
Incentive Stock Plan, A&R 2014 Plan, and 2023 Plan [Member]
Pertains to the plans.
Security Exchange Name
Title of 12(b) Security
us-gaap_ProceedsFromIssuanceOfLongTermDebt
Proceeds from Issuance of Long-Term Debt
Receivable Type [Axis]
Receivable [Domain]
Research and Development Expense [Member]
Statement of Income Location, Balance [Axis]
Statement of Income Location, Balance [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Schedule of Accounts, Notes, Loans and Financing Receivable [Table Text Block]
Auditor Name
Auditor Firm ID
Auditor Location
us-gaap_ContractualObligation
Contractual Obligation
us-gaap_RepaymentsOfNotesPayable
Repayments of Notes Payable
us-gaap_FinanceLeaseRightOfUseAssetAccumulatedAmortization
less: accumulated depreciation and amortization
Antidilutive securities (in shares)
us-gaap_FinanceLeaseRightOfUseAssetBeforeAccumulatedAmortization
Property and equipment, at cost
us-gaap_OperatingLossCarryforwards
Operating Loss Carryforwards
Asset Class [Axis]
Asset Class [Domain]
Statement [Table]
Statement of Financial Position [Abstract]
zvra_OperatingLossCarryforwardsNotSubjectToExpiration
Operating Loss Carryforwards, Not Subject to Expiration
Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws that are not subject to expiration.
Officers compensation
Basic and diluted (in shares)
Weighted average number of shares of common stock outstanding, basic and diluted (in shares)
Common stock issued as a result of stock warrants exercised (in shares)
The number of shares issued during the period from exercises of warrants.
Other
Cost of product revenue (excluding $6,235 and $772 in intangible asset amortization for the years ended December 31, 2024, and 2023, respectively, shown separately below)
us-gaap_EffectiveIncomeTaxRateContinuingOperations
Federal income tax provision effective rate
Business Acquisition [Axis]
Change in rate
Basic and diluted net loss per share of common stock (in dollars per share)
Net loss (in dollars per share)
zvra_OperatingLossCarryforwardsSubjectToExpiration
Operating Loss Carryforwards, Subject to Expiration
Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws that are subject to expiration.
Business Acquisition, Acquiree [Domain]
Change in valuation allowance
Basic and diluted net loss per share of common stock:
Statement of Cash Flows [Abstract]
us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High
Statement of Stockholders' Equity [Abstract]
Income Statement [Abstract]
Other comprehensive income
Other comprehensive income (loss)
2027
The 2023 Plan [Member]
Represents the 2023 Employment Inducement Award Plan.
2028
2029
Canceled or forfeited, aggregate intrinsic value
Amount of accumulated difference between fair value of underlying shares on dates of exercise and exercise price on options forfeited or expired.
us-gaap_BusinessCombinationContingentConsiderationLiability
Business Combination, Contingent Consideration, Liability
Balance
Balance
Proceeds from issuance of debt
Proceeds from Issuance of Debt
Pre-launch Inventory that Qualified for Capitalization [Member]
Represents pre-launch inventory that qualified for capitalization.
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths
2025
us-gaap_RepaymentsOfDebt
Repayment of debt
us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo
2026
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Interest on lease liabilities
us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares (in shares)
174 expenses
Amount, before allocation of valuation allowance, of deferred tax asset attributable to 174 expenses.
Loss on sublease and disposal of property and equipment
Represents the loss on sublease and disposal of property and equipment recognized during the period.
Schedule of Inventory, Noncurrent [Table Text Block]
Amortization of right-of-use assets
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Property and Equipment, Including Finance Leases [Member]
Represents property and equipment, including finance leases.
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Stock-based compensation
us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
Asset Acquisition [Axis]
us-gaap_AssetAcquisitionConsiderationTransferred
Asset Acquisition, Consideration Transferred
Interest and other income, net
Represents the amount of interest and other income (expense), net, recognized during the period.
Finance leases
State tax benefit (net of federal)
Foreign rate differential
us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
Research and development credit
Cash flows from financing activities:
us-gaap_AssetAcquisitionConsiderationTransferredEquityInterestIssuedAndIssuable
Asset Acquisition, Consideration Transferred, Equity Interest Issued and Issuable
Schedule of Common Stock Outstanding Roll Forward [Table Text Block]
Warrants [Member]
Information pertaining to warrants.
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Federal statutory rate
Other long-term liabilities
Asset Acquisition [Domain]
Change in Accounting Estimate by Type [Axis]
Change in Accounting Estimate, Type [Domain]
Intangible Assets, Amortization Period [Member]
Consulting fees paid in common stock
The amount of consulting fees are paid in stock.
Corporate Bond Securities [Member]
Fair value adjustment related to investments
zvra_FairValueAdjustmentOfInvestments
Fair value adjustment related to investments
Amount of expense (income) related to adjustment to fair value of investments.
zvra_IncreaseDecreaseInOperatingLeaseRightofuseAsset
Operating lease right-of-use assets
The amount of increase (decrease) in operating lease right-of-use assets.
us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet
Fair Value of Net Assets Acquired
Current portion of discount and rebate liabilities
Current portion of discount and rebate liabilities.
Discount and rebate liabilities, less current portion
Noncurrent portion of discount and rebate liabilities.
us-gaap_StockholdersEquity
Total stockholders' equity
Balance
Balance
us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities
Income tax payable, noncurrent
us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired
Acquisitions, net
Class of Stock [Axis]
Class of Stock [Domain]
Long-term debt
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets
Discount and rebate liabilities
Increase (decrease) in discount and rebate liabilities.
Operating Segments [Member]
Upper range (in dollars per share)
Derivative Financial Instruments, Liabilities [Member]
Other receivables
Exercise Price Range [Axis]
Exercise Price Range [Domain]
Property, plant, and equipment
Other noncurrent assets
Lower range (in dollars per share)