Document And Entity Information
us-gaap_NontradeReceivables
Nontrade Receivables
Note To Financial Statement Details Textual
Significant Accounting Policies
Maturities of investments
Note C - Segment Information
Note D - Inventories
us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Note E - Debt Obligations
us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five
Note F - Revenue, Net
Note G - Stock and Warrants
Note H - Stock-based Compensation
Note I - Fair Value of Financial Instruments
Note J - Net Loss Per Share
Note K - Leases
zvra_EmployeeStockPurchasePlanMaximumNumberOfIssuableShares
Employee Stock Purchase Plan, Maximum Number of Issuable Shares (in shares)
Maximum number of shares that may be issued under Employee Stock Purchase Plan.
Note L - Goodwill & Intangible Assets
Note C - Segment Information - Operating Segment Results (Details)
Note D - Inventories - Summary of Inventory (Details)
us-gaap_LiabilitiesCurrent
Total current liabilities
Note E - Debt Obligations - Aggregate Principal Amount (Details)
Schedule of Maturities of Long-Term Debt [Table Text Block]
Note E - Debt Obligations - Future Minimum Principal Payments (Details)
Note F - Revenue, Net - Schedule of Accounts and Other Receivables (Details)
Note G - Stock and Warrants - Reserved Authorized Shares of Common Stock for Future Issuance (Details)
Note G - Stock and Warrants - Common Stock Activity (Details)
Other current liabilities
Note H - Stock-based Compensation - Stock-based Compensation Expense (Details)
Note I - Fair Value of Financial Instruments - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)
Note I - Fair Value of Financial Instruments - Fair Value Assumptions for Warrant Liabilities (Details)
Note I - Fair Value of Financial Instruments - Reconciliation of Beginning and Ending Balances for Derivative and Warrant Liability Measured at Fair Value on Recurring Basis (Details)
Note J - Net Loss Per Share - Anti-dilutive Securities (Details)
Note J - Net Loss Per Share - Earnings Per Share (Details)
Note K - Leases - Lease Cost (Details)
Note K - Leases - Supplement Cash Flow Information Related to Leases (Details)
Note K - Leases - Supplement Balance Sheet Information Related to Lease (Details)
Note K - Leases - Supplement Balance Sheet Information Related to Lease (Details) (Parentheticals)
Note K - Leases - Maturities of Lease Liabilities (Details)
Note L - Goodwill & Intangible Assets - Amortization of Intangible Assets (Details)
Notes To Financial Statements
Arimoclomol Purchase Agreement [Member]
Represents Arimoclomol Purchase Agreement.
Notes To Financial Statements [Abstract]
US Treasury Securities [Member]
Foreign currency translation adjustment
zvra_AssetAcquisitionConsiderationTransferredEstimatedReserveLiability
Asset Acquisition, Consideration Transferred, Estimated Reserve Liability
Represents estimated reserve liability for asset acquisition consideration transferred.
zvra_ContractWithCustomerClawbackLiability
Contract with Customer, Clawback Liability
Represents clawback liability for contract with customer
Other comprehensive (loss) income:
us-gaap_PaymentsToAcquireOtherInvestments
Purchases of investments
zvra_SharesAndWarrantsIssuedPricePerShare
Shares and Warrants Issued, Price Per Share (in dollars per share)
The price per share of shares and warrants issued.
us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent
Accounts payable and accrued expenses
Goodwill and Intangible Assets Disclosure [Text Block]
zvra_EquityDistributionAgreementMaximumAggregateOfferingPrice
Equity Distribution Agreement, Maximum Aggregate Offering Price
The maximum aggregate offering price under the equity distribution agreement.
zvra_EquityDistributionAgreementCommissionFeePercentageOfGrossSales
Equity Distribution Agreement, Commission Fee, Percentage of Gross Sales
The percentage of gross sales for commission fee under the equity distribution agreement.
zvra_PaymentsOfPrincipalOnInsuranceFinancingArrangements
Payments of principal on insurance financing arrangements
Represents payments of principal on insurance financing arrangements.
us-gaap_PolicyTextBlockAbstract
Accounting Policies
us-gaap_PaymentsToAcquireIntangibleAssets
Payments to Acquire Intangible Assets
us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Purchases of property and equipment
us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized (in shares)
Costs accrued in connection with the debt issuance
Liabilities and stockholders' equity
us-gaap_LossContingencyAccrualAtCarryingValue
Loss Contingency Accrual
Weighted average number of shares of common stock outstanding:
Operating lease liabilities
us-gaap_Assets
Total assets
Supplemental cash flow information:
Patents [Member]
Plan Name [Axis]
Plan Name [Domain]
us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic
Net loss
us-gaap_SubleaseIncome
Less: sublease income
us-gaap_DebtInstrumentVariableInterestRateTypeExtensibleEnumeration
Debt Instrument, Variable Interest Rate, Type [Extensible Enumeration]
Share-Based Payment Arrangement [Text Block]
Finite-Lived Intangible Assets by Major Class [Axis]
Finite-Lived Intangible Assets, Major Class Name [Domain]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
ATM Agreement Sales [Member]
Represents for At-the-Market Agreement Sales.
Business Description and Basis of Presentation [Text Block]
Award Type [Domain]
Award Type [Axis]
Segment net loss
Net loss
Net loss
Net loss, basic and diluted
us-gaap_FiniteLivedIntangibleAssetsNet
Finite-Lived Intangible Assets, Net
Intangible assets, net
Performance Shares [Member]
Share-Based Payment Arrangement [Member]
Warrant [Member]
Inventory [Axis]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
zvra_IncomeTaxExpenseBenefitNoncashAdjustment
Income tax expense
The amount of noncash adjustment due to income tax expense (benefit).
Inventory [Domain]
Antidilutive Securities [Axis]
Antidilutive Securities, Name [Domain]
Underwriting Agreement [Member]
Represents the information pertaining to the underwriting agreement.
us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill
Indefinite-Lived Intangible Assets (Excluding Goodwill)
zvra_ProceedsFromIssuanceOfCommonStockNet
Proceeds from Issuance of Common Stock, Net
The cash inflow from issuance of common stock, net of cash paid for issuance cost.
Commitments and Contingencies Disclosure [Text Block]
Property, Plant and Equipment, Net
Goodwill
Goodwill
Derivative Instrument [Axis]
Derivative Contract [Domain]
Cash flows from investing activities:
Earnings Per Share [Text Block]
zvra_ClassOfWarrantsOrRightExercisedDuringPeriod
Class of Warrants or Right, Exercised During Period (in shares)
The number of warrants or rights exercised during period.
us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Accounts payable and accrued expenses
Income tax expense (benefit)
us-gaap_IncomeTaxExpenseBenefit
Income tax (expense) benefit
Consolidation, Variable Interest Entity, Policy [Policy Text Block]
XOMA License Agreement [Member]
Information pertaining to the type of arrangement.
Warrants [Policy Text Block]
Represents the policy for warrants.
Aquestive Therapeutics [Member]
Represents Aquestive Therapeutics (formerly known as MonoSol Rx, LLC).
AZSTARYS License Agreement [Member]
Information pertaining to the litigation.
Cash and cash equivalents
Interest expense
us-gaap_InterestExpenseNonoperating
Interest expense
us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities
Other liabilities
ZVRA_ Timothy J. Sangiovanni [Member]
Information pertaining to insider trading.
Stock based compensation expense
Share-Based Payment Arrangement, Expense
ZVRA_R. LaDuane Clifton [Member]
Information pertaining to insider trading.
ZVRA_ Neil F. McFarlane [Member]
Information pertaining to insider trading.
ZVRA_ Joshua Schafer [Member]
Information pertaining to insider trading.
Amendment Flag
us-gaap_ComprehensiveIncomeNetOfTax
Comprehensive loss
City Area Code
Use of Estimates, Policy [Policy Text Block]
New Accounting Pronouncements, Policy [Policy Text Block]
Common stock, shares outstanding (in shares)
Common Stock, Shares, Outstanding (in shares)
Balance (in shares)
Balance (in shares)
Commave Therapeutics SA [Member]
Named other party that participates in a financial transaction. Examples include, but not limited to, the name of the financial institution.
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding (in shares)
Possible Future Issuances Under Employee Stock Purchase Plans [Member]
Represents possible future issuances under employee stock purchase plans.
Warrant liability
Derivative and Warrant Liability, Noncurrent
Noncurrent Carrying amount of derivative and warrant liability.
Current Fiscal Year End Date
us-gaap_DebtInstrumentBasisSpreadOnVariableRate1
Debt Instrument, Basis Spread on Variable Rate
Variable lease cost
us-gaap_LeaseCost
Total lease costs
us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Prepaid expenses and other current assets
Operating leases
Document Fiscal Period Focus
Operating lease cost
Document Fiscal Year Focus
Short-term lease cost
Lease, Cost [Table Text Block]
Right-of-use assets obtained in exchange for lease liabilities
Document Period End Date
us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
Operating leases
Operating leases (in years) (Year)
Entity File Number
Entity Emerging Growth Company
us-gaap_DebtInstrumentFaceAmount
Debt Instrument, Face Amount
Document Type
Interim Period, Costs Not Allocable [Domain]
Entity Small Business
Entity Shell Company
Document Information [Line Items]
Document Information [Table]
us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue
Balance
Balance
Nature of Expense [Axis]
Entity Filer Category
Debt Instrument [Axis]
Entity Current Reporting Status
Debt Instrument, Name [Domain]
us-gaap_ImpairmentOfIntangibleAssetsFinitelived
Impairment of Intangible Assets, Finite-Lived
Commercial Trade Accounts Receivable [Member]
Amount due from customers or clients for goods or services that have been delivered or sold in the normal course of business.
SIFMA Municipal Swap Rate [Member]
Royalties and Milestones Receivables [Member]
Relates to Royalties and milestones receivables.
Product Reimbursements [Member]
Relates to product reimbursements.
Variable Rate [Domain]
Change in fair value measurement
Amount of cumulative effect adjustment for financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.
Acer and Relief Therapeutics SA [Member]
Represents Acer and Relief Therapeutics SA.
zvra_FairValueAdjustmentOfPutOptionNetOfTax
Fair Value Adjustment of Put Option, Net of Tax
After tax amount of expense (income) related to adjustment to fair value of put option.
ZVRA_ Rahsaan Thompson [Member]
Information pertaining to insider trading.
Schedule of Long-Term Debt Instruments [Table Text Block]
Contingent Consideration [Member]
Relates to contingent consideration liabilities.
Other Receivables [Member]
Relates to other receivables.
Stock-based compensation expense
us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables
Accounts and other receivables
Statement of Comprehensive Income [Abstract]
Entity Tax Identification Number
ZVRA_ Adrian W. Quartel [Member]
Information pertaining to insider trading.
Entity Central Index Key
Capitalized Contract Cost [Axis]
Common Stock Warrant Liabilities [Member]
Pertains to warrants.
Entity Registrant Name
Capitalized Contract Cost [Domain]
Liability Class [Axis]
Fair Value by Liability Class [Domain]
Entity [Domain]
Legal Entity [Axis]
Entity Address, Address Line One
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Amortization of intangible assets
Amortization of Intangible Assets
ecd_NonRule10b51ArrTrmntdFlag
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Entity Address, City or Town
ecd_Rule10b51ArrTrmntdFlag
Rule 10b5-1 Arrangement Terminated [Flag]
ecd_Rule10b51ArrAdoptedFlag
Rule 10b5-1 Arrangement Adopted [Flag]
Entity Address, Postal Zip Code
Entity Address, State or Province
ecd_NonRule10b51ArrAdoptedFlag
Non-Rule 10b5-1 Arrangement Adopted [Flag]
us-gaap_AllowanceForDoubtfulAccountsReceivable
Accounts Receivable, Allowance for Credit Loss
Material Terms of Trading Arrangement [Text Block]
us-gaap_TreasuryStockValue
Treasury stock, at cost
ecd_TrdArrIndTitle
Trading Arrangement, Individual Title
ecd_TrdArrIndName
Trading Arrangement, Individual Name
ecd_TrdArrTerminationDate
Trading Arrangement Termination Date
ecd_TrdArrSecuritiesAggAvailAmt
Trading Arrangement, Securities Aggregate Available Amount
Entity Common Stock, Shares Outstanding
Trading Arrangements, by Individual [Table]
ecd_TrdArrAdoptionDate
Trading Arrangement Adoption Date
us-gaap_IncreaseDecreaseInInventories
Inventories
Trading Symbol
us-gaap_StockIssuedDuringPeriodSharesAcquisitions
Stock Issued During Period, Shares, Acquisitions (in shares)
us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans
Stock Issued During Period, Shares, Employee Stock Purchase Plans (in shares)
Local Phone Number
Common stock issued as a result of stock options exercised or released (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period (in shares)
us-gaap_TableTextBlock
Notes Tables
Issuance of common stock as part of the Employee Stock Purchase Plan
Issuance of common stock for options exercised or released
Selling, general and administrative
Selling, general and administrative
zvra_DebtInstrumentMinimumCashBalance
Debt Instrument, Minimum Cash Balance
Minimum cash balance required for debt instrument to be active.
Secured Overnight Financing Rate (SOFR) [Member]
Measurement Input
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
zvra_CommonStockRegisteredMaximumOfferingPrice
Common Stock Registered, Maximum Offering Price
Represents maximum offering price under common stock registered.
JMP [Member]
Represents JMP.
us-gaap_StockIssuedDuringPeriodSharesNewIssues
Stock Issued During Period, Shares, New Issues (in shares)
Issuance of common stock in exchange for consulting services
us-gaap_StockIssuedDuringPeriodSharesIssuedForServices
Common stock issued as compensation to third parties (in shares)
us-gaap_LiabilitiesAndStockholdersEquity
Total liabilities and stockholders' equity
UNITED STATES
Underwriting Agreement and Over-allotment Option [Member]
Represents Underwriting Agreement and Over-allotment Option.
zvra_StockIssuableDuringThePeriod
Stock Issuable During the Period (in shares)
Number of stock issuable during the period.
Accumulated deficit
Accumulated other comprehensive (loss) income
Research and development
Research and development
Debt Disclosure [Text Block]
Measurement Input, Price Volatility [Member]
Change in assets and liabilities:
Measurement Input, Risk Free Interest Rate [Member]
Schedule of Authorized Shares of Common Stock Reserved for Future Issuance [Table Text Block]
Tabular disclosure of authorized shares of common stock reserved for future issuance.
us-gaap_DisclosureTextBlockAbstract
Notes to Financial Statements
Inventory Disclosure [Text Block]
Subsequent Event [Member]
Measurement Input, Expected Dividend Rate [Member]
Operating lease liabilities, less current portion
Measurement Input, Expected Term [Member]
Possible Future Issuances Under Equity Incentive Plans [Member]
Represents possible future issuances under equity incentive plans.
us-gaap_OperatingLeaseLiability
Lease liabilities
Total operating lease liabilities
Non-cash interest expense
Subsequent Event Type [Axis]
Current portion of operating lease liabilities
Subsequent Event Type [Domain]
Subsequent Events [Text Block]
Total operating lease right-of-use assets
Operating lease right-of-use assets
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue
Total lease payments
zvra_SharebasedCompensationArrangementBySharebasedPaymentAwardNumberOfSharesReservedForIssuanceIncrementalPercentageOfCapitalStockOutstanding
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Reserved for Issuance, Incremental Percentage of Capital Stock Outstanding
Represents the share based compensation arrangement by share based payment award number of shares reserved for issuance incremental percentage of capital stock outstanding.
us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
Less: future interest expense
2014 Equity Incentive Plan [Member]
Represents the two thousand fourteen equity incentive plan.
zvra_IncreaseInCommonStockReservedForIssuance
Increase in Common Stock Reserved for Issuance (in shares)
Amount of increase in common stock reserved for issuance.
Measurement Input Type [Axis]
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree
2028
Measurement Input Type [Domain]
2025 (excluding the three months ended March 31, 2025)
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour
2029
us-gaap_UnrealizedGainLossOnInvestments
Unrealized Gain (Loss) on Investments
us-gaap_FinanceLeaseRightOfUseAsset
Property and equipment, net
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Acer Warrants [Member]
Represents the Acer warrants.
Net Investment in Lease, before Allowance for Credit Loss
2027
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo
zvra_CommonStockRegisteredShares
Common Stock Registered, Shares (in shares)
Shares registered as apart of an S-3 filing.
2028
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree
2029
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
2026
us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
2027
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Segment Reporting, Policy [Policy Text Block]
2026
us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths
The Investor Warrant [Member]
Represents the warrant held by the investor.
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Relief Therapeutics [Member]
Relates to Relief Therapeutics.
Warrants to Purchase Common Stock [Member]
Represents warrants to purchase common stock.
Other long-term assets
us-gaap_ShareBasedCompensation
Stock-based compensation expense
us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear
2025 (excluding the three months ended March 31, 2025)
us-gaap_FiniteLivedIntangibleAssetUsefulLife
Finite-Lived Intangible Asset, Useful Life (Year)
Operating expenses:
zvra_RoyaltyRevenuePercent
Royalty Revenue, Percent
Represents the royalty revenue expressed as a percentage.
Total assets
zvra_RevenueRecognitionMilestoneMethodAdditionalRevenueToBeRecognized
Revenue Recognition, Milestone Method, Additional Revenue to be Recognized
The amount of additional consideration to be recognized for the milestone or milestones.
us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments
Accretion on investments
Securities at fair value, noncurrent
Total liabilities
Depreciation and amortization expense
Depreciation and amortization expense
CVR Liability [Member]
Represents the CVR liability.
us-gaap_SharesIssuedPricePerShare
Shares Issued, Price Per Share (in dollars per share)
Inventories, noncurrent
us-gaap_AssetsCurrent
Total current assets
zvra_FinanceLeaseCostTotal
Total finance lease cost
Represents total cost of fiance lease.
us-gaap_InvestmentsFairValueDisclosure
Investments, Fair Value Disclosure
Equity [Text Block]
zvra_LesseeLeaseRemainingTermOfContract
Lessee, Lease, Remaining Term of Contract (Year)
Remaining term of lessee's lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.
Lease Disclosure [Text Block]
The entire disclosure for operating, finance, sale leaseback leases.
Weighted average fair value (in dollars per share)
Represents the weighted average fair value under fair value assumptions for warrant liabilities.
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Common stock, $0.0001 par value, 250,000,000 shares authorized, 56,255,055 shares issued and 54,679,363 shares outstanding as of March 31, 2025; 55,246,401 shares issued and 53,670,709 shares outstanding as of December 31, 2024
Measurement Frequency [Axis]
Adjustments to reconcile net loss to net cash used in operating activities:
Measurement Frequency [Domain]
Fair Value, Recurring [Member]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized (in shares)
Common stock, shares issued (in shares)
Common Stock, Shares, Issued (in shares)
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share (in dollars per share)
Schedule of Leases Cash Flow Information [Table Text Block]
Tabular disclosure of leases related to cash flow information.
Revenue from Contract with Customer [Policy Text Block]
Schedule of Leases Balance Sheet Information [Table Text Block]
Tabular disclosure of leases related to balance sheet.
Common shares reserved for future issuance (in shares)
Statistical Measurement [Domain]
Term Loans Under Credit Agreement [Member
Represents term loans under credit agreement.
Operating cash flows from operating leases
Maximum [Member]
zvra_DebtInstrumentAvailableAmountUntilDecember312024
Debt Instrument, Available Amount Until December 31, 2024
Amount of debt available to be drawn until December 31, 2024.
zvra_DebtInstrumentNetProductSalesPerformanceBenchmark
Debt Instrument, Net Product Sales Performance Benchmark
Amount of performance benchmark of net product sales under debt instrument.
Minimum [Member]
zvra_DebtInstrumentBasisSpreadOnVariableRateWhenPerformanceBenchmarkMeet
Debt Instrument, Basis Spread on Variable Rate When Performance Benchmark Meet
Percentage points added to the reference rate to compute the variable rate on the debt instrument when performance benchmark meet.
Product and Service [Axis]
Operating cash flows from short-term leases
Product and Service [Domain]
zvra_DebtInstrumentAvailableAmountUntil18MonthsFollowingClosingDateMaximumEachDrawing
Debt Instrument, Available Amount Until 18 Months Following Closing Date, Maximum Each Drawing
Maximum each drawing for amount available under debt instrument to draw after 18 months of debt closing date.
Fair value adjustment related to warrant and CVR liability
Fair value adjustment related to warrant and CVR liability
Amount of expense (income) related to adjustment to fair value of warrant liability and CVR Liability
Operating cash flows from variable lease costs
Statistical Measurement [Axis]
zvra_DebtInstrumentAvailableAmountUntil18MonthsFollowingClosingDate
Debt Instrument, Available Amount Until 18 Months Following Closing Date
Amount of debt available until 18 months following closing date under debt instrument.
Operating and Finance Lease, Liability, Maturity [Table Text Block]
Tabular disclosure of undiscounted cash flows of operating and finance lease liability. Includes, but is not limited to, reconciliation of undiscounted cash flows to operating and finance lease liability recognized in statement of financial position.
Debt, Policy [Policy Text Block]
Undesignated preferred stock, $0.0001 par value, 10,000,000 shares authorized, no shares issued or outstanding as of March 31, 2025, or December 31, 2024
zvra_DebtInstrumentBasisSpreadOnVariableRateWhenPerformanceBenchmarkMeetInNextYear
Debt Instrument, Basis Spread on Variable Rate When Performance Benchmark Meet in Next Year
Percentage points added to the reference rate to compute the variable rate on the debt instrument when performance benchmark meet in next year.
Preferred stock, shares issued (in shares)
Preferred Stock, Shares Issued (in shares)
zvra_DebtInstrumentNetProductSalesPerformanceBenchmarkInNextYear
Debt Instrument, Net Product Sales Performance Benchmark in Next Year
Amount of performance benchmark of net product sales in next year under debt instrument.
zvra_DebtInstrumentMaximumInterestPaymentPercentage
Debt Instrument, Maximum Interest Payment, Percentage
Maximum amount of interest payment allowed under debt instrument as a percentage.
Cash paid for interest
zvra_DebtInstrumentFloorRate
Debt Instrument, Floor Rate
Floor rate of debt instrument.
us-gaap_NoncurrentAssets
Long-Lived Assets
Geographical [Axis]
Geographical [Domain]
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized (in shares)
Europe [Member]
OLPRUVA [Member]
Represents OLPRUVA.
zvra_LesseeLeaseOptionToTerminateTerm
Lessee, Lease, Option to Terminate, Term (Year)
Represents the terms of option to terminate lessee's lease.
Inventories, current
Inventory, Net
zvra_LesseeLeaseOptionToExtendMaximumTerm
Lessee, Lease, Option to Extend, Maximum Term (Year)
Represents maximum terms of option to extend lessee's lease.
Preferred stock, par value (in dollars per share)
Work in progress
Total revenues
Revenue, net
Revenue from Contract with Customer, Including Assessed Tax
Fair Value, Inputs, Level 3 [Member]
us-gaap_ForeignCurrencyTransactionGainLossBeforeTax
Loss on foreign currency exchange rates
Finished goods
Fair Value Hierarchy and NAV [Domain]
Fair Value, Inputs, Level 1 [Member]
Fair Value, Inputs, Level 2 [Member]
Fair Value Hierarchy and NAV [Axis]
Raw materials
Cash flows from operating activities:
Accounts and other receivables
Accounts and other receivables
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Statement [Line Items]
us-gaap_NumberOfOperatingSegments
Number of Operating Segments
Additional paid-in capital
AOCI Attributable to Parent [Member]
Stockholders’ equity:
Securities at fair value, current
Other income, net(a)
us-gaap_OtherNonoperatingIncomeExpense
us-gaap_NonoperatingIncomeExpense
Total other income
Segment Reporting Disclosure [Text Block]
Other income (expense):
Fair Value Disclosures [Text Block]
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
Cash and cash equivalents, beginning of period
Cash and cash equivalents, end of period
Inventory, Policy [Policy Text Block]
Assets [Abstract]
License [Member]
Effect of exchange rate changes on cash and cash equivalents
us-gaap_InvestmentIncomeInterest
Interest income
us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
Net increase (decrease) in cash and cash equivalents
Over-Allotment Option [Member]
us-gaap_Liabilities
Total liabilities
us-gaap_NetCashProvidedByUsedInFinancingActivities
Net cash provided by financing activities
Commitments and contingencies (Note M)
Sale of Stock [Axis]
Sale of Stock [Domain]
us-gaap_OperatingIncomeLoss
Loss from operations
us-gaap_ContractWithCustomerLiabilityRevenueRecognized
Contract with Customer, Liability, Revenue Recognized
us-gaap_NetCashProvidedByUsedInOperatingActivities
Net cash used in operating activities
Prepaid expenses and other current assets
us-gaap_NetCashProvidedByUsedInInvestingActivities
Net cash provided by investing activities
Counterparty Name [Axis]
Counterparty Name [Domain]
Consolidation Items [Domain]
us-gaap_ContractWithCustomerLiability
Contract with Customer, Liability
Consolidation Items [Axis]
us-gaap_InterestPayableCurrentAndNoncurrent
Interest Payable
Intangible asset amortization
Investment, Policy [Policy Text Block]
us-gaap_CostsAndExpenses
Total operating expenses
Cost of Goods and Service [Policy Text Block]
us-gaap_ProceedsFromWarrantExercises
Proceeds from Warrant Exercises
Retained Earnings [Member]
Undesignated Preferred Stock [Member]
Preferred stock that has been classified as undesignated.
Proceeds from issuance of common stock for options exercised
Proceeds from stock issuance
Treasury Stock, Common [Member]
Additional Paid-in Capital [Member]
Common Stock [Member]
Equity Components [Axis]
MIPLYFFA [Member]
Pertains to MIPLYFFA.
Equity Component [Domain]
Relief License Agreement [Member]
Pertains to the Relief License Agreement.
Class of Warrant or Right [Axis]
Class of Warrant or Right [Domain]
Long-term debt
us-gaap_NotesPayable
Notes Payable
us-gaap_ClassOfWarrantOrRightOutstanding
Class of Warrant or Right, Outstanding (in shares)
us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
Income (loss) before income taxes
us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)
Capitalization, Royalty Expense [Member]
Pertains to capitalized costs.
us-gaap_DeferredFinanceCostsNet
Debt Issuance Costs, Net
Less: debt issuance costs
us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
Less: unamortized debt discount, debt issuance costs and paid in kind interest
us-gaap_DeferredRevenue
Deferred Revenue
Indirect Operating Costs [Member]
Information pertaining to the nature of the expense.
Direct Operating Costs [Member]
Information pertaining to the nature of the expense.
Revenue from Contract with Customer [Text Block]
zvra_InventoryCurrentAndNoncurrentTotal
Total inventories
Represents inventory.
us-gaap_DebtInstrumentUnamortizedDiscountPremiumNet
Unamortized original issue discount
PRV Transfer Agreement [Member]
Pertains to the type of arrangement.
Document Quarterly Report
Entity Incorporation, State or Country Code
Notes payable
us-gaap_DebtInstrumentCarryingAmount
Total minimum payments
Accounting Policies [Abstract]
Significant Accounting Policies [Text Block]
Document Transition Report
Selling, General and Administrative Expenses [Member]
Entity Interactive Data Current
Security Exchange Name
Title of 12(b) Security
Receivable Type [Axis]
Receivable [Domain]
All Individuals [Member]
Research and Development Expense [Member]
Statement of Income Location, Balance [Axis]
Statement of Income Location, Balance [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Individual [Axis]
Schedule of Accounts, Notes, Loans and Financing Receivable [Table Text Block]
us-gaap_ContractualObligation
Contractual Obligation
us-gaap_FinanceLeaseRightOfUseAssetAccumulatedAmortization
Less: accumulated depreciation and amortization
Antidilutive securities (in shares)
us-gaap_FinanceLeaseRightOfUseAssetBeforeAccumulatedAmortization
Property and equipment, at cost
Asset Class [Axis]
Asset Class [Domain]
Statement [Table]
Statement of Financial Position [Abstract]
Basic and diluted (in shares)
Weighted average number of shares of common stock outstanding, basic and diluted (in shares)
Warrants issued as a result of stock warrants exercised (in shares)
The number of shares issued during the period from exercises of warrants.
Cost of product revenue (excluding $1,615 and $1,528 in intangible asset amortization for the three months ended March 31, 2025, and March 31, 2024, respectively, shown separately below)
Business Combination [Axis]
Basic and diluted net loss per share of common stock (in dollars per share)
Net loss (in dollars per share)
Business Combination [Domain]
Basic and diluted net loss per share of common stock:
Statement of Cash Flows [Abstract]
2025 (excluding the three months ending March 31, 2025)
Statement of Stockholders' Equity [Abstract]
Income Statement [Abstract]
Other comprehensive loss
Other comprehensive (loss) income
2028
The 2023 Plan [Member]
Represents the 2023 Employment Inducement Award Plan.
2029
us-gaap_ProceedsFromIssuanceOfDebt
Proceeds from Issuance of Debt
Pre-launch Inventory that Qualified for Capitalization [Member]
Represents pre-launch inventory that qualified for capitalization.
2026
2027
Schedule of Inventory, Noncurrent [Table Text Block]
Amortization of right-of-use assets
Asset Acquisition [Axis]
Interest and other income, net
Represents the amount of interest and other income (expense), net, recognized during the period.
Cash flows from financing activities:
Schedule of Common Stock Outstanding Roll Forward [Table Text Block]
Warrants [Member]
Information pertaining to warrants.
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Other long-term liabilities
Asset Acquisition [Domain]
Consulting fees paid in common stock
The amount of consulting fees are paid in stock.
Corporate Bond Securities [Member]
Fair value adjustment related to investments
zvra_FairValueAdjustmentOfInvestments
Fair value adjustment related to investments
Amount of expense (income) related to adjustment to fair value of investments.
zvra_IncreaseDecreaseInOperatingLeaseRightofuseAsset
Operating lease right-of-use assets
The amount of increase (decrease) in operating lease right-of-use assets.
zvra_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour
Thereafter
Amount of lessee's undiscounted obligation for lease payment for operating lease due after fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).
Current portion of discount and rebate liabilities
Current portion of discount and rebate liabilities.
Discount and rebate liabilities, less current portion
Noncurrent portion of discount and rebate liabilities.
us-gaap_StockholdersEquity
Total stockholders' equity
Balance
Balance
Income tax payable
Class of Stock [Axis]
Class of Stock [Domain]
Long-term debt
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Discount and rebate liabilities
Increase (decrease) in discount and rebate liabilities.
Operating Segments [Member]
Derivative Financial Instruments, Liabilities [Member]